产品货号：
Z25392
中文名称：
RIMS2抗体
英文名称：
Anti-RIMS2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RIMS2 Antibody |
| 指标别名 | OBOE;RIM2;RAB3IP3;KIAA0751;Regulating synaptic membrane exocytosis protein 2;Rab-3-interacting molecule 2;RIM 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | RIMS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rim2 antibody was raised against a 17 amino acid synthetic peptide near the center of the human Rim2.The immunogen is located within amino acids 250 - 300 of Rim2. |
| 计算分子量 | 160kDa |
| 成分 | Rim2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Rim2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity.Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain.While the ablation of either gene was not lethal in mice,the deletion of both resulted in postnatal mortality.This lethality is due to a defect in neurotransmitter release;synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers.Like Rim1,Rim 2 is thought to be an effector protein for Rab3,binding to Rab3 on synaptic vesicles in a GTP-dependent manner. |
| Uniprot ID | Q9UQ26 |
| 基因名全称 | Regulating synaptic membrane exocytosis 2 |
| 蛋白名全称 | Regulating synaptic membrane exocytosis 2 |
| 推荐稀释比 | Rim2 antibody can be used for detection of Rim2 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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